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The antibody against ELOA2 was raised in rabbit using the Synthetic peptide of Human TCEB3B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against ELOA2 was raised in rabbit using the Synthetic peptide of Human TCEB3B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-25717A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ELOA2 |
| Target Synonyms | ELOA2 antibody; TCEB3B antibody; TCEB3LElongin-A2 antibody; EloA2 antibody; RNA polymerase II transcription factor SIII subunit A2 antibody; Transcription elongation factor B polypeptide 3B antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human TCEB3B | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IYF1 |
Uniprot Id
Q8IYF1
Target Species
Human
Target Name
ELOA2
Target Full Name
Elongin-A2
Target Function
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Specifically expressed in testis.
Target Synonyms
HsT832; TCEB3B; TCEB3L
Target Background
This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.
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