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Rabbit anti-Human RAB39B Polyclonal Antibody

The antibody against RAB39B was raised in rabbit using the Synthetic peptide of Human RAB39B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-26287A

The antibody against RAB39B was raised in rabbit using the Synthetic peptide of Human RAB39B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-26287A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRAB39B
Target SynonymsRAB39B antibody; Ras-related protein Rab-39B antibodyFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human RAB39BTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ96DA2
Background Information
  • Uniprot Id

    Q96DA2

  • Target Species

    Human

  • Target Name

    RAB39B

  • Target Full Name

    Ras-related protein Rab-39B

  • Target Function

    Small GTPases Rab involved in autophagy. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. May regulate the homeostasis of SNCA/alpha-synuclein. Together with PICK1 proposed to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR compostion at the post-synapses and thus synaptic transmission.

  • Target Involvement

    Mental retardation, X-linked 72 (MRX72); Waisman syndrome (WSMN)

  • Target Subcellular Location

    Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus.

  • Target Protein Families

    Small GTPase superfamily, Rab family

  • Target Tissue Specificity

    Highly expressed in the brain.

  • Target Synonyms

    RAB39B; Ras-related protein Rab-39B

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