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The antibody against MTBP was raised in rabbit using the Synthetic peptide of Human MTBP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against MTBP was raised in rabbit using the Synthetic peptide of Human MTBP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-26337A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MTBP |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human MTBP | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96DY7 |
Uniprot Id
Q96DY7
Target Species
Human
Target Name
MTBP
Target Full Name
Mdm2-binding protein
Target Function
Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
Target Protein Families
MTBP family
Target Synonyms
hMTBP; MDM 2 binding protein; MDM 2 BP; MDM2 (mouse double minute 2) binding protein 104kD; MDM2 (mouse double minute 2) binding protein; MDM2 binding protein; MDM2 BP; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein binding protein; Mdm2-binding protein; MDM2BP; Mouse double minute 2 homolog binding protein; MTBP; MTBP_HUMAN
Target Background
This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation.
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