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The antibody against BBC3 was raised in rabbit using the Synthetic peptide of Human BBC3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against BBC3 was raised in rabbit using the Synthetic peptide of Human BBC3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-28750A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BBC3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human BBC3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BXH1 |
Uniprot Id
Q9BXH1
Target Species
Human
Target Name
BBC3
Target Full Name
Bcl-2-binding component 3, isoforms 1/2
Target Function
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Target Subcellular Location
Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release.
Target Protein Families
Bcl-2 family
Target Tissue Specificity
Ubiquitously expressed.
Target Synonyms
BBC 3; Bbc3; BBC3_HUMAN; BCL 2 binding component 3; Bcl-2-binding component 3; BCL2 binding component 3; JFY 1; JFY-1; JFY1; p53 up regulated modulator of apoptosis; p53 up-regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; PUMA alpha; PUMA/JFY1
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