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The antibody against RAI14 was raised in rabbit using the Recombinant Human Ankycorbin protein (242-346AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RAI14 was raised in rabbit using the Recombinant Human Ankycorbin protein (242-346AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-03149A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RAI14 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ankycorbin protein (242-346AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9P0K7 |
Uniprot Id
Q9P0K7
Target Species
Human
Target Name
RAI14
Target Full Name
Ankycorbin
Target Function
Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cell junction. Nucleus.
Target Tissue Specificity
Highly expressed in placenta, muscle, kidney and testis. Moderately expressed in heart, brain, lung, liver and intestine. Isoform 2 is widely expressed and expressed in fetal and adult testes, and spermatozoa.
Target Synonyms
Ankycorbin; Ankyrin repeat and coiled coil structure containing protein; Ankyrin repeat and coiled-coil structure-containing protein; DKFZp564G013; KIAA1334; NORPEG; Novel retinal pigment epithelial cell protein; RAI13; RAI14; RAI14_HUMAN; Retinoic acid induced 14; Retinoic acid induced protein 14; Retinoic acid-induced protein 14
Target Background
Predicted to enable actin binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm.
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