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Rabbit anti-Human DHCR7 Polyclonal Antibody

The antibody against DHCR7 was raised in rabbit using the Fusion protein of Human DHCR7 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-30194A

The antibody against DHCR7 was raised in rabbit using the Fusion protein of Human DHCR7 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-30194A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDHCR7
Target SynonymsDHCR7; D7SR; 7-dehydrocholesterol reductase; 7-DHC reductase; Delta7-sterol reductase; Sterol Delta(7-reductase; Sterol reductase SR-2FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human DHCR7Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UBM7
Background Information
  • Uniprot Id

    Q9UBM7

  • Target Species

    Human

  • Target Name

    DHCR7

  • Target Full Name

    7-dehydrocholesterol reductase

  • Target Function

    7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway.

  • Target Involvement

    Smith-Lemli-Opitz syndrome (SLOS)

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Protein Families

    ERG4/ERG24 family

  • Target Tissue Specificity

    Widely expressed. Most abundant in adrenal gland, liver, testis, and brain.

  • Target Synonyms

    DHCR7; D7SR; 7-dehydrocholesterol reductase; 7-DHC reductase; Delta7-sterol reductase; Sterol Delta(7-reductase; Sterol reductase SR-2

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