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Rabbit anti-Human H3F3C Polyclonal Antibody

The antibody against H3F3C was raised in rabbit using the Fusion protein of Human H3F3C as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-31861A

The antibody against H3F3C was raised in rabbit using the Fusion protein of Human H3F3C as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$299.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-31861A ClonalityPolyclonal
Host SpeciesRabbitTarget NameH3F3C
Target Synonymsfamily 3C antibody; H3.5 antibody; H3C_HUMAN antibody; h3f3c antibody; Histone H3.3C antibody; Histone H3.5 antibody; Histone variant H3.5 antibody, H3 histoneFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human H3F3CTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6NXT2
Background Information
  • Uniprot Id

    Q6NXT2

  • Target Species

    Human

  • Target Name

    H3-5

  • Target Full Name

    Histone H3.3C

  • Target Function

    Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Hominid-specific H3.5/H3F3C preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes.

  • Target Subcellular Location

    Nucleus. Chromosome.

  • Target Protein Families

    Histone H3 family

  • Target Tissue Specificity

    Specifically expressed in the seminiferous tubules of testis.

  • Target Synonyms

    H3 histone, family 3C; H3.5; H3C_HUMAN; h3f3c; Histone H3.3C; Histone H3.5; Histone variant H3.5

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