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The antibody against ABCB5 was raised in rabbit using the Fusion protein of Human ABCB5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against ABCB5 was raised in rabbit using the Fusion protein of Human ABCB5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-32367A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ABCB5 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human ABCB5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q2M3G0 |
Uniprot Id
Q2M3G0
Target Species
Human
Target Name
ABCB5
Target Full Name
ATP-binding cassette sub-family B member 5
Target Function
Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily
Target Tissue Specificity
Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Highly expressed in several malignant tissues: highly expressed in clinical melanomas, with low expr
Target Synonyms
ABCB 5; ABCB5; ABCB5 P-gp; ABCB5_HUMAN; ABCB5alpha; ABCB5beta; ATP binding cassette protein; ATP binding cassette sub family B (MDR/TAP) member 5; ATP binding cassette sub family B member 5; ATP-binding cassette sub-family B member 5; EST422562; P glycoprotein ABCB5; P-glycoprotein ABCB5
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