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The antibody against UPK3B was raised in rabbit using the Fusion protein of Human UPK3B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against UPK3B was raised in rabbit using the Fusion protein of Human UPK3B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-32582A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UPK3B |
| Target Synonyms | FLJ32198 antibody; MGC10902 antibody; p35 antibody; UP3b antibody; UPIIIb antibody; UPK3B antibody; UPK3B_HUMAN antibody; uroplakin 3B antibody; Uroplakin IIIb antibody; Uroplakin-3b antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human UPK3B | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BT76 |
Uniprot Id
Q9BT76
Target Species
Human
Target Name
UPK3B
Target Full Name
Uroplakin-3b
Target Function
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Uroplakin-3 family
Target Synonyms
FLJ32198; MGC10902; p35; UP3b; UPIIIb; UPK3B; UPK3B_HUMAN; uroplakin 3B; Uroplakin IIIb; Uroplakin-3b
Target Background
UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).
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