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The antibody against SLC6A11 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GABA T-3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against SLC6A11 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GABA T-3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
| Cat.No | ADC-34079A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC6A11 |
| Target Synonyms | GABT3 antibody; GAT-3 antibody; GAT3 antibody; S6A11_HUMAN antibody; Slc6a11 antibody; Sodium- and chloride-dependent GABA transporter 3 antibody; Solute carrier family 6 member 11 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human GABA T-3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P48066 |
Uniprot Id
P48066
Target Species
Human
Target Name
SLC6A11
Target Full Name
Sodium- and chloride-dependent GABA transporter 3
Target Function
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A11 subfamily
Target Tissue Specificity
Widespread distribution in the brain.
Target Synonyms
GABT3; GAT-3; GAT3; S6A11_HUMAN; Slc6a11; Sodium- and chloride-dependent GABA transporter 3; Solute carrier family 6 member 11
Target Background
The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene.
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