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The antibody against GNRH1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GnRH I. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against GNRH1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GnRH I. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-35573A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GNRH1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human GnRH I. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01148 |
Uniprot Id
P01148
Target Species
Human
Target Name
GNRH1
Target Full Name
Progonadoliberin-1
Target Function
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
Target Involvement
Hypogonadotropic hypogonadism 12 with or without anosmia (HH12)
Target Subcellular Location
Secreted.
Target Protein Families
GnRH family
Target Synonyms
GNRH1; GNRH; GRH; LHRHProgonadoliberin-1; Progonadoliberin I) [Cleaved into: Gonadoliberin-1; Gonadoliberin I; Gonadorelin; Gonadotropin-releasing hormone I; GnRH-I; Luliberin I; Luteinizing hormone-releasing hormone I; LH-RH I); GnRH-associated peptide 1; GnRH-associated peptide I)]
Target Background
This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism.
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