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The antibody against PRAG1 was raised in rabbit using the Synthesized peptide derived from Human Pragmin around the phosphorylation site of Y413. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against PRAG1 was raised in rabbit using the Synthesized peptide derived from Human Pragmin around the phosphorylation site of Y413. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of A549 cells using Phospho-Pragmin (Y413) Polyclonal Antibody
| Cat.No | ADC-36185A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRAG1 |
| Target Synonyms | Chr 8, D8Ertd82e antibody; DKFZp761P0423 antibody; DNA segment | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human Pragmin around the phosphorylation site of Y413. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86YV5 |
Uniprot Id
Q86YV5
Target Species
Human
Target Name
PRAG1
Target Full Name
Inactive tyrosine-protein kinase PRAG1
Target Function
Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth. Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism. Acts as a critical coactivator of Notch signaling.
Target Subcellular Location
Cytoplasm. Cell junction, focal adhesion. Nucleus.
Target Protein Families
Protein kinase superfamily
Target Synonyms
D8Ertd82e; DKFZp761P0423; DNA segment, Chr 8, ERATO Doi 82; EC 2.7.10.2; Homolog of rat pragma of Rnd2; LOC157285; PRAGMIN ; SG223_HUMAN; Sgk223; Sugen kinase 223; Tyrosine protein kinase SgK223; Tyrosine-protein kinase SgK223
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