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Rabbit anti-Human SLC24A4 Polyclonal Antibody

The antibody against SLC24A4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NCKX4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-36414A

The antibody against SLC24A4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NCKX4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-36414A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLC24A4
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human NCKX4.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8NFF2
Background Information
  • Uniprot Id

    Q8NFF2

  • Target Species

    Human

  • Target Name

    SLC24A4

  • Target Full Name

    Sodium/potassium/calcium exchanger 4

  • Target Function

    Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis.

  • Target Involvement

    Amelogenesis imperfecta, hypomaturation type, 2A5 (AI2A5)

  • Target Subcellular Location

    Cytoplasm. Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family, SLC24A subfamily

  • Target Tissue Specificity

    Expressed abundantly in all regions of the brain, aorta, lung and thymus. Expressed at lower levels in the stomach and intestine.

  • Target Synonyms

    Na(+)/K(+)/Ca(2+)-exchange protein 4; NCKX4; NCKX4_HUMAN; SHEP6; SLC24A2; SLC24A4; Sodium/potassium/calcium exchanger 4; Solute carrier family 24 (sodium/potassium/calcium exchanger) member 4; Solute carrier family 24 member 4

  • Target Background

    Enables calcium, potassium:sodium antiporter activity. Involved in calcium ion transmembrane transport; potassium ion transmembrane transport; and sodium ion transmembrane transport. Acts upstream of or within cellular calcium ion homeostasis. Part of plasma membrane. Implicated in amelogenesis imperfecta hypomaturation type 2A5.

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