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Rabbit anti-Human SYP Polyclonal Antibody

The antibody against SYP was raised in rabbit using the Synthesized peptide derived from the Internal region of Human SYP. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-37526A

The antibody against SYP was raised in rabbit using the Synthesized peptide derived from the Internal region of Human SYP. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-37526A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSYP
Target SynonymsSYP; Synaptophysin; Major synaptic vesicle protein p38FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human SYP.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP08247
Background Information
  • Uniprot Id

    P08247

  • Target Species

    Human

  • Target Name

    SYP

  • Target Full Name

    Synaptophysin

  • Target Function

    Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.

  • Target Involvement

    Mental retardation, X-linked 96 (MRX96)

  • Target Subcellular Location

    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.

  • Target Protein Families

    Synaptophysin/synaptobrevin family

  • Target Tissue Specificity

    Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    SYP; Synaptophysin; Major synaptic vesicle protein p38

  • Target Background

    This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability.

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