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Rabbit anti-Human PFKM Polyclonal Antibody

The antibody against PFKM was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PFKM. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-37873A

The antibody against PFKM was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PFKM. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-37873A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePFKM
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human PFKM.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP08237
Background Information
  • Uniprot Id

    P08237

  • Target Species

    Human

  • Target Name

    PFKM

  • Target Full Name

    ATP-dependent 6-phosphofructokinase, muscle type

  • Target Function

    Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.

  • Target Involvement

    Glycogen storage disease 7 (GSD7)

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Phosphofructokinase type A (PFKA) family, ATP-dependent PFK group I subfamily, Eukaryotic two domain clade "E" sub-subfamily

  • Target Synonyms

    6 Phosphofructokinase Muscle Type; 6-phosphofructokinase; 6-phosphofructokinase muscle type; EC 2.7.1.1; EC 2.7.1.11; GSD7; K6PF_HUMAN; MGC8699; muscle type; PFK; muscle type; PFK-A; PFKA; PFKL; PFKM; PFKP; PFKX; Phosphofructo 1 Kinase Isozyme A; Phosphofructo-1-kinase isozyme A; Phosphofructokinase 1; Phosphofructokinase M; Phosphofructokinase; muscle; Phosphofructokinase; muscle type; Phosphofructokinase; polypeptide X; Phosphofructokinase-M; Phosphohexokinase

  • Target Background

    Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

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