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The antibody against KCNC4 was raised in rabbit using the Synthesized peptide derived from Human Kv3.4 around the non-phosphorylation site of S15. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against KCNC4 was raised in rabbit using the Synthesized peptide derived from Human Kv3.4 around the non-phosphorylation site of S15. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
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Western Blot analysis of SH-SY5Y cells using Kv3.4 Polyclonal Antibody
Western Blot analysis of Jurkat cells using Kv3.4 Polyclonal Antibody2
| Cat.No | ADC-38340A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KCNC4 |
| Target Synonyms | KCNC4 antibody; C1orf30 antibody; Potassium voltage-gated channel subfamily C member 4 antibody; KSHIIIC antibody; Voltage-gated potassium channel subunit Kv3.4 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Monkey | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human Kv3.4 around the non-phosphorylation site of S15. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q03721 |
Uniprot Id
Q03721
Target Species
Human
Target Name
KCNC4
Target Full Name
Voltage-gated potassium channel KCNC4
Target Function
This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Potassium channel family, C (Shaw) (TC 1.A.1.2) subfamily, Kv3.4/KCNC4 sub-subfamily
Target Synonyms
KV3.4; C1orf30; KSHIIIC; HKSHIIIC; KCNC4
Target Background
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene.
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