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The antibody against AASS was raised in rabbit using the Synthesized peptide derived from the Internal region of Human AASS. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against AASS was raised in rabbit using the Synthesized peptide derived from the Internal region of Human AASS. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of HeLa cells using AASS Polyclonal Antibody
Western Blot analysis of 293 NIH-3T3 A549 cells using AASS Polyclonal Antibody2
| Cat.No | ADC-39419A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AASS |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human AASS. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UDR5 |
Uniprot Id
Q9UDR5
Target Species
Human
Target Name
AASS
Target Full Name
Alpha-aminoadipic semialdehyde synthase, mitochondrial
Target Function
Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.
Target Involvement
Hyperlysinemia, 1 (HYPLYS1); 2,4-dienoyl-CoA reductase deficiency (DECRD)
Target Subcellular Location
Mitochondrion.
Target Protein Families
AlaDH/PNT family; Saccharopine dehydrogenase family
Target Tissue Specificity
Expressed in all 16 tissues examined with highest expression in the liver.
Target Synonyms
AASSAlpha-aminoadipic semialdehyde synthase; mitochondrial; LKR/SDH) [Includes: Lysine ketoglutarate reductase; LKR; LOR; EC 1.5.1.8); Saccharopine dehydrogenase; SDH; EC 1.5.1.9)]
Target Background
This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
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