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Rabbit anti-Human Acetyl-Histone H2B (K5) Polyclonal Antibody

The antibody against H2BFS was raised in rabbit using the Synthesized peptide derived from Human Histone H2B around the acetylation site of K5. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

ADC-39887A

The antibody against H2BFS was raised in rabbit using the Synthesized peptide derived from Human Histone H2B around the acetylation site of K5. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-39887A ClonalityPolyclonal
Host SpeciesRabbitTarget NameH2BFS
Target SynonymsH2BFS antibody; Histone H2B type F-S antibody; Histone H2B.s antibody; H2B/s antibodyFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Human Histone H2B around the acetylation site of K5.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP57053
Background Information
  • Uniprot Id

    P57053

  • Target Species

    Human

  • Target Name

    H2BC12L

  • Target Full Name

    Histone H2B type F-S

  • Target Function

    Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

  • Target Subcellular Location

    Nucleus. Chromosome.

  • Target Protein Families

    Histone H2B family

  • Target Synonyms

    H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s

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