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The antibody against POU5F1B was raised in rabbit using the Recombinant Human Putative POU domain, class 5, transcription factor 1B protein (10-138AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against POU5F1B was raised in rabbit using the Recombinant Human Putative POU domain, class 5, transcription factor 1B protein (10-138AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-04932A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | POU5F1B |
| Target Synonyms | class 5, transcription factor 1B antibody; transcription factor 1B antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Putative POU domain, class 5, transcription factor 1B protein (10-138AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q06416 |
Uniprot Id
Q06416
Target Species
Human
Target Name
POU5F1B
Target Full Name
Putative POU domain, class 5, transcription factor 1B
Target Function
Shows weak transcriptional activator activity.
Target Subcellular Location
Nucleus.
Target Protein Families
POU transcription factor family, Class-5 subfamily
Target Tissue Specificity
Detected at the mRNA level in several cancer tissues (breast, uterine cervix, lung, thyroid gland, esophagus, colon, urinary bladder, and glioma), but absent in normal tissues.
Target Synonyms
OTF3C; OTF3P1; OCT4PG1; OCT4-PG1; POU5F1P1; POU5F1P4; POU5FLC8; POU5FLC20; POU5F1B
Target Background
This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.
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