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Rabbit anti-Human POU3F1 Polyclonal Antibody

The antibody against POU3F1 was raised in rabbit using the Synthesized peptide derived from internal of Human OCT6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-41995A

The antibody against POU3F1 was raised in rabbit using the Synthesized peptide derived from internal of Human OCT6. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-41995A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePOU3F1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human OCT6.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ03052
Background Information
  • Uniprot Id

    Q03052

  • Target Species

    Human

  • Target Name

    POU3F1

  • Target Full Name

    POU domain, class 3, transcription factor 1

  • Target Function

    Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    POU transcription factor family, Class-3 subfamily

  • Target Tissue Specificity

    Expressed in embryonal stem cells and in the developing brain.

  • Target Synonyms

    OCT6; OTF6; SCIP; POU3F1

  • Target Background

    Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of gene expression; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within keratinocyte differentiation; nervous system development; and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm.

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