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The antibody against AFF1 was raised in rabbit using the Synthesized peptide derived from N-terminal of Human AF4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC.
The antibody against AFF1 was raised in rabbit using the Synthesized peptide derived from N-terminal of Human AF4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using AF4 antibody.
| Cat.No | ADC-42038A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AFF1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from N-terminal of Human AF4. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51825 |
Uniprot Id
P51825
Target Species
Human
Target Name
AFF1
Target Full Name
AF4/FMR2 family member 1
Target Involvement
A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with KMT2A/MLL1. The result is a rogue activator protein.
Target Subcellular Location
Nucleus.
Target Protein Families
AF4 family
Target Synonyms
AF 4; AF 4 protein; AF4; AF4-MLL; AF4/FMR2 family member 1; AFF 1; AFF1; AFF1_HUMAN; ALL1 fused gene from chromosome 4; ALL1-fused gene from chromosome 4 protein; FEL; MGC134969; MLL/AF4; MLLT2; myeloid/lymphoid or mixed lineage leukemia (trithorax homolog; Drosophila); translocated to; 2; MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA TRANSLOCATED TO 2; MLLT2; PBM1; Pre B cell monocytic leukemia partner 1; Protein AF-4; Protein FEL; Proto-oncogene AF4
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