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The antibody against CKM was raised in rabbit using the Synthesized peptide derived from N-terminal of Human M-CK. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against CKM was raised in rabbit using the Synthesized peptide derived from N-terminal of Human M-CK. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
$297.00
Western blot analysis of extracts from HUVEC cells, HepG2 cells, Jurkat cells and HeLa cells, using M-CK antibody.
Immunohistochemistry analysis of paraffin-embedded human heart tissue using M-CK antibody.2
Immunofluorescence analysis of HepG2 cells, using M-CK antibody.3
| Cat.No | ADC-42170A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CKM |
| Target Synonyms | muscle type antibody; KCRM_HUMAN antibody; M-CK antibody; MCK antibody; Muscle creatine kinase antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from N-terminal of Human M-CK. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P06732 |
Uniprot Id
P06732
Target Species
Human
Target Name
CKM
Target Full Name
Creatine kinase M-type
Target Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Target Subcellular Location
Cytoplasm.
Target Protein Families
ATP:guanido phosphotransferase family
Target Research Area
Cancer
Target Synonyms
(Creatine kinase M chain)(Creatine phosphokinase M-type)(CPK-M)(M-CK)
Target Background
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
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