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The antibody against FLI1 was raised in rabbit using the Synthesized peptide derived from Human FLI1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against FLI1 was raised in rabbit using the Synthesized peptide derived from Human FLI1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
$297.00
Western blot analysis of extracts from NIH/3T3 cells, using FLI1 antibody.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FLI1 antibody.2
| Cat.No | ADC-42412A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FLI1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human FLI1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q01543 |
Uniprot Id
Q01543
Target Species
Human
Target Name
FLI1
Target Full Name
Friend leukemia integration 1 transcription factor
Target Function
Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.
Target Involvement
Ewing sarcoma (ES); Bleeding disorder, platelet-type 21 (BDPLT21)
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Research Area
Cancer
Target Synonyms
(Proto-oncogene Fli-1)(Transcription factor ERGB)
Target Background
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.
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