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The antibody against HIST3H3 was raised in rabbit using a synthetic methylated peptide corresponding to residues surrounding K4 of Human histone H3 as the immunogen. This antibody exists as a polyclonal antibody to the immunogen, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF, IP, ChIP.
The antibody against HIST3H3 was raised in rabbit using a synthetic methylated peptide corresponding to residues surrounding K4 of Human histone H3 as the immunogen. This antibody exists as a polyclonal antibody to the immunogen, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF, IP, ChIP.
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Western blot analysis of extracts of HeLa cell line and H3 protein expressed in E.coli., using H3K4me3 antibody.
Dot-blot analysis of all sorts of methylation peptides using H3K4me3 antibody.2
Immunofluorescence analysis of 293T cell using H3K4me3 antibody. Blue: DAPI for nuclear staining.3
| Cat.No | ADC-42941A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HIST3H3 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Application | ELISA, IF, IHC, WB, ChIP, IP | Storage | Upon receipt |
| Immunogen Description | A synthetic methylated peptide corresponding to residues surrounding K4 of Human histone H3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16695 |
Uniprot Id
Q16695
Target Species
Human
Target Name
H3-4
Target Full Name
Histone H3.1t
Target Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Histone H3 family
Target Tissue Specificity
Expressed in testicular cells.
Target Synonyms
HIST3H3; H3FT; Histone H3.1t; H3/t; H3t; H3/g
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