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The antibody against CRABP2 was raised in rabbit using the Peptide sequence around aa.87~91(K-W-E-S-E) derived from Human CRABP2 as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.
The antibody against CRABP2 was raised in rabbit using the Peptide sequence around aa.87~91(K-W-E-S-E) derived from Human CRABP2 as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from MCF-7 and HT-29 cells using CRABP2 Antibody.
| Cat.No | ADC-43125A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CRABP2 |
| Target Synonyms | cellular, type II antibody | Form | Liquid |
| Species Reactivity | Human, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence around aa.87~91(K-W-E-S-E) derived from Human CRABP2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P29373 |
Uniprot Id
P29373
Target Species
Human
Target Name
CRABP2
Target Full Name
Cellular retinoic acid-binding protein 2
Target Function
Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
Target Subcellular Location
Cytoplasm. Endoplasmic reticulum. Nucleus. Note=Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.
Target Protein Families
Calycin superfamily, Fatty-acid binding protein (FABP) family
Target Synonyms
Cellular retinoic acid binding protein 2; Cellular retinoic acid binding protein II; Cellular retinoic acid-binding protein 2; Cellular retinoic acid-binding protein II; CRABP II; CRABP-II; Crabp2; CRABPII; RABP2_HUMAN; RBP6; Rretinoic acid-binding protein, cellular, type II
Target Background
This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
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