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The antibody against Gripap1 was raised in rabbit using the Peptide sequence around aa. 814-818(Q-E-I-V-R ) derived from Rat GRASP. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide This antibody has been validated on ELISA, WB.
The antibody against Gripap1 was raised in rabbit using the Peptide sequence around aa. 814-818(Q-E-I-V-R ) derived from Rat GRASP. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from rat brain and mouse brain tissue using GRASP Antibody
| Cat.No | ADC-43207A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Gripap1 |
| Target Synonyms | Gripap1 antibody; Grasp1GRIP1-associated protein 1 antibody; GRASP-1) [Cleaved into: GRASP-1 C-terminal chain antibody; 30kDa C-terminus form)] antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence around aa. 814-818(Q-E-I-V-R ) derived from Rat GRASP. | Target Species | Rattus norvegicus (Rat) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9JHZ4 |
Uniprot Id
Q9JHZ4
Target Species
Rat
Target Name
GRIPAP1
Target Full Name
GRIP1-associated protein 1
Target Function
Regulates the endosomal recycling back to the neuronal plasma membrane, possibly by connecting early and late recycling endosomal domains and promoting segregation of recycling endosomes from early endosomal membranes. Involved in the localization of recycling endosomes to dendritic spines, thereby playing a role in the maintenance of dendritic spine morphology. Required for the activity-induced AMPA receptor recycling to dendrite membranes and for long-term potentiation and synaptic plasticity.; Functions as a scaffold protein in neurons to facilitate MAP3K1/MEKK1-mediated activation of the JNK1 kinase by phosphorylation, possibly by bringing MAP3K1/MEKK1 and JNK1 in close proximity.
Target Subcellular Location
Early endosome membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse.
Target Tissue Specificity
Expressed in the central nervous system; especially in neurons.
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