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The antibody against LMCD1 was raised in rabbit using the Recombinant Human LIM and cysteine-rich domains protein 1 protein (105-268AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against LMCD1 was raised in rabbit using the Recombinant Human LIM and cysteine-rich domains protein 1 protein (105-268AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-05418A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LMCD1 |
| Target Synonyms | Dyxin antibody; LIM and cysteine rich domains 1 antibody; LIM and cysteine rich domains protein 1 antibody; LIM and cysteine-rich domains protein 1 antibody; LMCD1 antibody; LMCD1_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human LIM and cysteine-rich domains protein 1 protein (105-268AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NZU5 |
Uniprot Id
Q9NZU5
Target Species
Human
Target Name
LMCD1
Target Full Name
LIM and cysteine-rich domains protein 1
Target Function
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Tissue Specificity
Expressed in the heart (at protein level). Expressed in many tissues with highest abundance in skeletal muscle.
Target Synonyms
Dyxin; LIM and cysteine rich domains 1; LIM and cysteine rich domains protein 1; LIM and cysteine-rich domains protein 1; LMCD1; LMCD1_HUMAN
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