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The antibody against RASSF7 was raised in rabbit using the Recombinant Human Ras association domain-containing protein 7 protein (300-368AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against RASSF7 was raised in rabbit using the Recombinant Human Ras association domain-containing protein 7 protein (300-368AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-05458A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RASSF7 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ras association domain-containing protein 7 protein (300-368AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q02833 |
Uniprot Id
Q02833
Target Species
Human
Target Name
RASSF7
Target Full Name
Ras association domain-containing protein 7
Target Function
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with gamma-tubulin.
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