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The antibody against HSPB2 was raised in rabbit using the Recombinant Human Heat shock protein beta-2 protein (1-182AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against HSPB2 was raised in rabbit using the Recombinant Human Heat shock protein beta-2 protein (1-182AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human heart tissue using HSPB2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using HSPB2 Antibody at dilution of 1:1002
| Cat.No | ADC-43975A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HSPB2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Heat shock protein beta-2 protein (1-182AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16082 |
Uniprot Id
Q16082
Target Species
Human
Target Name
HSPB2
Target Full Name
Heat shock protein beta-2
Target Function
May regulate the kinase DMPK.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Localizes to nuclear foci.
Target Protein Families
Small heat shock protein (HSP20) family
Target Tissue Specificity
Expressed preferentially in skeletal muscle and heart but not in the lens.
Target Research Area
Signal Transduction
Target Synonyms
DMPK-binding protein; Heat shock 27kD protein 2; Heat shock 27kDa protein 2; Heat shock protein beta-2; Heat-shock protein beta-2; Hs.78846; HSP27; HspB2; HSPB2_HUMAN; LOH11CR1K; MGC133245; MKBP
Target Background
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function.
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