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The antibody against GEM was raised in rabbit using the Recombinant Human GTP-binding protein GEM protein (1-150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against GEM was raised in rabbit using the Recombinant Human GTP-binding protein GEM protein (1-150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human breast cancer using GEM Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using GEM Antibody at dilution of 1:1002
| Cat.No | ADC-44419A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GEM |
| Target Synonyms | GEM antibody; KIRGTP-binding protein GEM antibody; GTP-binding mitogen-induced T-cell protein antibody; RAS-like protein KIR antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human GTP-binding protein GEM protein (1-150AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P55040 |
Uniprot Id
P55040
Target Species
Human
Target Name
GEM
Target Full Name
GTP-binding protein GEM
Target Function
Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
Target Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
Small GTPase superfamily, RGK family
Target Tissue Specificity
Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle.
Target Synonyms
GEM; KIRGTP-binding protein GEM; GTP-binding mitogen-induced T-cell protein; RAS-like protein KIR
Target Background
The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
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