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The antibody against CTSG was raised in rabbit using the Recombinant Human Cathepsin G protein (21-255AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against CTSG was raised in rabbit using the Recombinant Human Cathepsin G protein (21-255AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human tonsil tissue using CTSG Antibody at dilution of 1:100
| Cat.No | ADC-44423A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CTSG |
| Target Synonyms | CATG antibody; CATG_HUMAN antibody; Cathepsin G antibody; Cathepsin G precursor antibody; CathepsinG antibody; CG antibody; Ctsg antibody; CTSG protein antibody; MGC23078 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cathepsin G protein (21-255AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P08311 |
Uniprot Id
P08311
Target Species
Human
Target Name
CTSG
Target Full Name
Cathepsin G
Target Function
Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Cleaves vimentin. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa.
Target Subcellular Location
Cell surface. Membrane; Peripheral membrane protein.
Target Protein Families
Peptidase S1 family
Target Research Area
Neuroscience
Target Synonyms
CATG; CATG_HUMAN; Cathepsin G; Cathepsin G precursor; CathepsinG; CG; Ctsg; CTSG protein; MGC23078
Target Background
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
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