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The antibody against CYGB was raised in rabbit using the Recombinant Human Cytoglobin protein (1-190AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against CYGB was raised in rabbit using the Recombinant Human Cytoglobin protein (1-190AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CYGB Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CYGB Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-44544A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CYGB |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cytoglobin protein (1-190AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WWM9 |
Uniprot Id
Q8WWM9
Target Species
Human
Target Name
CYGB
Target Full Name
Cytoglobin
Target Function
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Globin family
Target Tissue Specificity
Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine.
Target Research Area
Transport
Target Synonyms
Cygb; CYGB_HUMAN; Cytoglobin; Hgb; Histoglobin; STAP; Stellate cell activation associated protein ; Stellate cell activation-associated protein
Target Background
This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation.
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