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The antibody against SETD3 was raised in rabbit using the Recombinant Human Histone-lysine N-methyltransferase setd3 protein (166-265AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SETD3 was raised in rabbit using the Recombinant Human Histone-lysine N-methyltransferase setd3 protein (166-265AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-05653A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SETD3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Histone-lysine N-methyltransferase setd3 protein (166-265AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86TU7 |
Uniprot Id
Q86TU7
Target Species
Human
Target Name
SETD3
Target Full Name
Actin-histidine N-methyltransferase
Target Function
Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, SETD3 subfamily
Target Synonyms
C14orf154; Chromosome 14 open reading frame 154 ; DKFZp761E1415; FLJ23027; Histone lysine N methyltransferase setd3; Histone-lysine N-methyltransferase setd3; MGC87236; SET domain containing 3; SET domain containing protein 3; SET domain-containing protein 3; SETD 3; Setd3; SETD3_HUMAN
Target Background
Enables protein-L-histidine N-tele-methyltransferase activity. Involved in actin modification and peptidyl-histidine methylation. Located in cytoplasm.
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