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The antibody against COL10A1 was raised in rabbit using the Recombinant Human Collagen alpha-1(X) chain protein (521-680AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against COL10A1 was raised in rabbit using the Recombinant Human Collagen alpha-1(X) chain protein (521-680AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human prostate tissue using COL10A1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using COL10A1 Antibody at dilution of 1:1002
| Cat.No | ADC-44746A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COL10A1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Collagen alpha-1(X) chain protein (521-680AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q03692 |
Uniprot Id
Q03692
Target Species
Human
Target Name
COL10A1
Target Full Name
Collagen alpha-1(X) chain
Target Function
Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
Target Involvement
Schmid type metaphyseal chondrodysplasia (SMCD)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Synonyms
COL10A1; collagen alpha-1(X) chain
Target Background
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).
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