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The antibody against Selenot was raised in rabbit using the Recombinant Mouse Thioredoxin reductase-like selenoprotein T protein (20-195AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against Selenot was raised in rabbit using the Recombinant Mouse Thioredoxin reductase-like selenoprotein T protein (20-195AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-45565A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Selenot |
| Target Synonyms | Selenot antibody; Selt antibody; Thioredoxin reductase-like selenoprotein T antibody; SelT antibody; EC 1.8.1.9 antibody | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Thioredoxin reductase-like selenoprotein T protein (20-195AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P62342 |
Uniprot Id
P62342
Target Species
Mouse
Target Name
SELENOT
Target Full Name
Thioredoxin reductase-like selenoprotein T
Target Function
Selenoprotein with thioredoxin reductase-like oxidoreductase activity. Protects dopaminergic neurons against oxidative stress ans cell death. Involved in ADCYAP1/PACAP-induced calcium mobilization and neuroendocrine secretion. Plays a role in fibroblast anchorage and redox regulation. In gastric smooth muscle, modulates the contraction processes through the regulation of calcium release and MYLK activation. In pancreatic islets, involved in the control of glucose homeostasis, contributes to prolonged ADCYAP1/PACAP-induced insulin secretion.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families
SelWTH family, Selenoprotein T subfamily
Target Tissue Specificity
Ubiquitous. Highly expressed in the endocrine pancreas. Expressed at low levels in the adult brain.
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