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The antibody against RELT was raised in rabbit using the Recombinant Human Tumor necrosis factor receptor superfamily member 19L protein (26-153AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against RELT was raised in rabbit using the Recombinant Human Tumor necrosis factor receptor superfamily member 19L protein (26-153AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-45829A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RELT |
| Target Synonyms | Receptor expressed in lymphoid tissues antibody; Relt antibody; TNFRSF19L antibody; TR19L_HUMAN antibody; Tumor necrosis factor receptor superfamily member 19L antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tumor necrosis factor receptor superfamily member 19L protein (26-153AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q969Z4 |
Uniprot Id
Q969Z4
Target Species
Human
Target Name
RELT
Target Full Name
Tumor necrosis factor receptor superfamily member 19L
Target Function
May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel formation.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region.
Target Protein Families
RELT family
Target Tissue Specificity
Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas.
Target Research Area
Signal Transduction
Target Synonyms
Receptor expressed in lymphoid tissues; Relt; TNFRSF19L; TR19L_HUMAN; Tumor necrosis factor receptor superfamily member 19L
Target Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
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