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The antibody against ARR3 was raised in rabbit using the Human ARR3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against ARR3 was raised in rabbit using the Human ARR3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-46047A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARR3 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human ARR3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P36575 |
Uniprot Id
P36575
Target Species
Human
Target Name
ARR3
Target Full Name
Arrestin-C
Target Function
May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.
Target Subcellular Location
Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
Target Protein Families
Arrestin family
Target Tissue Specificity
Inner and outer segments, and the inner plexiform regions of the retina.
Target Synonyms
ARR3; ARR4; ARRC_HUMAN; Arrestin 3 retinal; Arrestin 3 retinal (X-arrestin); Arrestin 4; Arrestin-C; ARRX; C arrestin; C-arrestin; CAR; cArr; Cone arrestin; Retinal cone arrestin 3; Retinal cone arrestin-3; X arrestin; X-arrestin
Target Background
The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function.
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