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The antibody against TEP1 was raised in rabbit using the Recombinant Human Telomerase protein component 1 protein (2-226AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against TEP1 was raised in rabbit using the Recombinant Human Telomerase protein component 1 protein (2-226AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human breast cancer using TEP1 Antibody at dilution of 1: 100
Immunohistochemistry of paraffin-embedded human skin tissue using TEP1 Antibody at dilution of 1:1002
Immunohistochemistry of paraffin-embedded human esophageal tissue using TEP1 Antibody at dilution of 1: 1003
| Cat.No | ADC-46356A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TEP1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Telomerase protein component 1 protein (2-226AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99973 |
Uniprot Id
Q99973
Target Species
Human
Target Name
TEP1
Target Full Name
Telomerase protein component 1
Target Function
Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC.
Target Subcellular Location
Nucleus. Chromosome, telomere.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
TEP1; TLP1; TP1; Telomerase protein component 1; Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog
Target Background
This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants.
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