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Rabbit anti-Human HPRT1 Polyclonal Antibody, FITC conjugated

The antibody against HPRT1 was raised in rabbit using the Recombinant Human Hypoxanthine-guanine phosphoribosyltransferase protein (2-218AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

ADC-46391A

The antibody against HPRT1 was raised in rabbit using the Recombinant Human Hypoxanthine-guanine phosphoribosyltransferase protein (2-218AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

$299.00

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Specifications


Cat.No ADC-46391A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHPRT1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateFITC conjugated
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Hypoxanthine-guanine phosphoribosyltransferase protein (2-218AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP00492
Background Information
  • Uniprot Id

    P00492

  • Target Species

    Human

  • Target Name

    HPRT1

  • Target Full Name

    Hypoxanthine-guanine phosphoribosyltransferase

  • Target Function

    Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.

  • Target Involvement

    Lesch-Nyhan syndrome (LNS); Gout HPRT-related (GOUT-HPRT)

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Purine/pyrimidine phosphoribosyltransferase family

  • Target Research Area

    Metabolism

  • Target Synonyms

    HGPRT; HGPRTase; HPRT 1; HPRT_HUMAN; HPRT1; Hypoxanthine guanine phosphoribosyltransferase ; Hypoxanthine phosphoribosyltransferase 1 (Lesch Nyhan syndrome); Hypoxanthine phosphoribosyltransferase 1; Hypoxanthine-guanine phosphoribosyltransferase

  • Target Background

    The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.

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