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The antibody against XK was raised in rabbit using the Human XK as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against XK was raised in rabbit using the Human XK as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$600.00
| Cat.No | ADC-46690A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | XK |
| Target Synonyms | XK antibody; XKR1 antibody; XRG1 antibody; Membrane transport protein XK antibody; Kell complex 37 kDa component antibody; Kx antigen antibody; XK-related protein 1 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Human XK | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51811 |
Uniprot Id
P51811
Target Species
Human
Target Name
XK
Target Full Name
Endoplasmic reticulum membrane adapter protein XK
Target Function
May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.
Target Involvement
McLeod syndrome (MLS)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
XK family
Target Tissue Specificity
High levels in skeletal muscle, heart, brain, and pancreas; low levels in placenta, lung, liver, and kidney.
Target Synonyms
XK; XKR1; XRG1; Membrane transport protein XK; Kell complex 37 kDa component; Kx antigen; XK-related protein 1
Target Background
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.
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