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The antibody against SPRY3 was raised in rabbit using the Human SPRY3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against SPRY3 was raised in rabbit using the Human SPRY3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-47074A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPRY3 |
| Target Synonyms | SPRY3 antibody; Protein sprouty homolog 3 antibody; Spry-3 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human SPRY3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43610 |
Uniprot Id
O43610
Target Species
Human
Target Name
SPRY3
Target Full Name
Protein sprouty homolog 3
Target Function
Inhibits neurite branching, arbor length and neurite complexity. Inhibits EGF-mediated p42/44 ERK signaling. Negatively regulates the MAPK cascade, resulting in a reduction of extracellular matrix protein accumulation. May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Sprouty family
Target Tissue Specificity
Widely expressed; particularly in the fetal tissues. Expressed in the brain with expression the highest in Purkinje cells in the cerebellum (at protein level). Expressed in the myocardium of the heart.
Target Synonyms
SPRY3; Protein sprouty homolog 3; Spry-3
Target Background
Involved in negative regulation of MAPK cascade. Predicted to be located in membrane. Predicted to be active in cytosol.
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