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Rabbit anti-Human P4HA1 Polyclonal Antibody

The antibody against P4HA1 was raised in rabbit using the Human P4HA1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-47722A

The antibody against P4HA1 was raised in rabbit using the Human P4HA1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-47722A ClonalityPolyclonal
Host SpeciesRabbitTarget NameP4HA1
Target Synonyms2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), 2-oxoglutarate-4-dioxygenase subunit alpha-1 antibody; 4-hydroxylase, alpha I subunit antibody; 4-PH alpha-1 antibody; P4HA antibody; P4HA1 antibody; P4HA1_HUMAN antibody; Procollagen-proline antibody; Procollagen-proline, alpha polypeptide I antibody; Prolyl 4-hydroxylase subunit alpha-1 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman P4HA1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP13674
Background Information
  • Uniprot Id

    P13674

  • Target Species

    Human

  • Target Name

    P4HA1

  • Target Full Name

    Prolyl 4-hydroxylase subunit alpha-1

  • Target Function

    Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.

  • Target Subcellular Location

    Endoplasmic reticulum lumen.

  • Target Protein Families

    P4HA family

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    2-oxoglutarate-4-dioxygenase subunit alpha-1; 4-hydroxylase, alpha I subunit; 4-PH alpha-1; P4HA; P4HA1; P4HA1_HUMAN; Procollagen-proline; Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I; Prolyl 4-hydroxylase subunit alpha-1

  • Target Background

    This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

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