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Rabbit anti-Human IFI30 Polyclonal Antibody

The antibody against IFI30 was raised in rabbit using the Human IFI30 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-48278A

The antibody against IFI30 was raised in rabbit using the Human IFI30 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-48278A ClonalityPolyclonal
Host SpeciesRabbitTarget NameIFI30
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman IFI30Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP13284
Background Information
  • Uniprot Id

    P13284

  • Target Species

    Human

  • Target Name

    IFI30

  • Target Full Name

    Gamma-interferon-inducible lysosomal thiol reductase

  • Target Function

    Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation.

  • Target Subcellular Location

    Secreted. Lysosome.

  • Target Protein Families

    GILT family

  • Target Research Area

    Immunology

  • Target Synonyms

    Gamma interferon inducible lysosomal thiol reductase; Gamma interferon inducible protein IP 30 ; Gamma-interferon-inducible lysosomal thiol reductase; Gamma-interferon-inducible protein IP-30; GILT ; GILT_HUMAN; IFI 30; IFI30; interferon gamma inducible protein 30; Interferon gamma inducible protein 30 preproprotein ; IP30 ; Legumaturain; Lysosomal thiol reductase; Lysosomal thiol reductase; gamma-interferon-inducible

  • Target Background

    The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.

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