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The antibody against FUCA1 was raised in rabbit using the Human FUCA1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against FUCA1 was raised in rabbit using the Human FUCA1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$600.00
| Cat.No | ADC-48518A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Fuca1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Human FUCA1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04066 |
Uniprot Id
P04066
Target Species
Human
Target Name
FUCA1
Target Full Name
Tissue alpha-L-fucosidase
Target Function
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
Target Involvement
Fucosidosis (FUCA1D)
Target Subcellular Location
Lysosome.
Target Protein Families
Glycosyl hydrolase 29 family
Target Synonyms
Alpha L fucosidase I; Alpha L fucoside fucohydrolase; Alpha-L-fucosidase 1; Alpha-L-fucosidase I; Alpha-L-fucoside fucohydrolase 1; FUCA; FUCA1; FUCO_HUMAN; fucosidase; alpha-L; tissue; fucosidase; alpha-L- 1; tissue; Tissue alpha L fucosidase; Tissue alpha-L-fucosidase
Target Background
The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.
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