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The antibody against EXTL2 was raised in rabbit using the Human EXTL2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against EXTL2 was raised in rabbit using the Human EXTL2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48603A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EXTL2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human EXTL2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UBQ6 |
Uniprot Id
Q9UBQ6
Target Species
Human
Target Name
EXTL2
Target Full Name
Exostosin-like 2
Target Function
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.; [Processed exostosin-like 2]: Secreted. Note=A soluble form is found in the serum.
Target Protein Families
Glycosyltransferase 47 family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
4-N-acetylhexosaminyltransferase EXTL2; Alpha 1 4 N acetylhexosaminyltransferase EXTL2; Alpha 1; Alpha GalNAcT EXTL2; Alpha-1; Alpha-GalNAcT EXTL2; Exostoses (multiple) like 2; Exostoses multiple like 2; Exostosin like 2; Exostosin like glycosyltransferase 2; EXT L2; EXT related protein 2 ; EXT-related protein 2; EXTL 2; EXTL2; EXTL2_HUMAN; EXTR 2; EXTR2; Glucuronyl galactosyl proteoglycan 4 alpha N acetylglucosaminyltransferase; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostoses like 2; Processed exostosin like 2; Processed exostosin-like 2
Target Background
Enables alpha-1, 4-N-acetylgalactosaminyltransferase activity and glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Involved in N-acetylglucosamine metabolic process and UDP-N-acetylgalactosamine metabolic process. Located in cytosol; endoplasmic reticulum; and nucleoplasm.
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