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The antibody against HBA1 was raised in rabbit using the Recombinant Human Hemoglobin subunit alpha protein (2-142AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against HBA1 was raised in rabbit using the Recombinant Human Hemoglobin subunit alpha protein (2-142AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-49949A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HBA1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Hemoglobin subunit alpha protein (2-142AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P69905 |
Uniprot Id
P69905
Target Species
Human
Target Name
HBA1
Target Full Name
Hemoglobin subunit alpha
Target Function
Involved in oxygen transport from the lung to the various peripheral tissues.
Target Involvement
Heinz body anemias (HEIBAN); Alpha-thalassemia (A-THAL); Hemoglobin H disease (HBH)
Target Protein Families
Globin family
Target Tissue Specificity
Red blood cells.
Target Synonyms
HBH; ECYT7; HBA-T3; METHBA; Hemoglobin subunit alpha (HBA1)
Target Background
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
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