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The antibody against ANGPTL8 was raised in rabbit using the Recombinant Human Angiopoietin-like protein 8 protein (22-198AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against ANGPTL8 was raised in rabbit using the Recombinant Human Angiopoietin-like protein 8 protein (22-198AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver tissue using ANGPTL8 Antibody at dilution of 1:100
| Cat.No | ADC-50007A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Angptl8 |
| Target Synonyms | ANGPTL8 antibody; C19orf80 antibody; RIFL antibody; UNQ599/PRO1185Angiopoietin-like protein 8 antibody; Betatrophin antibody; Lipasin antibody; Refeeding-induced fat and liver protein antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Angiopoietin-like protein 8 protein (22-198AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6UXH0 |
Uniprot Id
Q6UXH0
Target Species
Human
Target Name
ANGPTL8
Target Full Name
Angiopoietin-like protein 8
Target Function
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state.
Target Involvement
Diabetes mellitus, insulin-dependent (IDDM); Diabetes mellitus, non-insulin-dependent (NIDDM)
Target Subcellular Location
Secreted.
Target Protein Families
ANGPTL8 family
Target Tissue Specificity
Predominantly expressed in liver. Also expressed in adipose tissues.
Target Research Area
Cell Biology
Target Synonyms
ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185Angiopoietin-like protein 8; Betatrophin; Lipasin; Refeeding-induced fat and liver protein
Target Background
Predicted to enable hormone activity. Involved in regulation of lipid metabolic process and triglyceride homeostasis. Acts upstream of or within positive regulation of protein processing and regulation of lipoprotein metabolic process. Located in extracellular region.
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