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The antibody against HDGF was raised in rabbit using the Recombinant Human Hepatoma-derived growth factor protein (1-239AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against HDGF was raised in rabbit using the Recombinant Human Hepatoma-derived growth factor protein (1-239AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-50819A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HDGF |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | HRP conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Hepatoma-derived growth factor protein (1-239AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51858 |
Uniprot Id
P51858
Target Species
Human
Target Name
HDGF
Target Full Name
Hepatoma-derived growth factor
Target Function
Acts as a transcriptional repressor. Has mitogenic activity for fibroblasts. Heparin-binding protein.; Does not have mitogenic activity for fibroblasts. Does not bind heparin.; Has mitogenic activity for fibroblasts. Heparin-binding protein.
Target Subcellular Location
[Isoform 1]: Nucleus. Cytoplasm. Secreted, extracellular exosome.; [Isoform 2]: Nucleus. Cytoplasm. Secreted, extracellular exosome.; [Isoform 3]: Nucleus. Cytoplasm. Secreted, extracellular exosome.
Target Protein Families
HDGF family
Target Tissue Specificity
Ubiquitous.
Target Research Area
Cancer
Target Synonyms
FLJ96580; HDGF; HDGF_HUMAN; Hepatoma derived growth factor; Hepatoma-derived growth factor; High mobility group protein 1 like 2; High mobility group protein 1-like 2; HMG-1L2; HMG1L2
Target Background
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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