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The antibody against TNPO2 was raised in rabbit using the Human TNPO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against TNPO2 was raised in rabbit using the Human TNPO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-51549A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TNPO2 |
| Target Synonyms | Importin 3 antibody; IPO3 antibody; Karyopherin beta 2b, isoform CRA b antibody; Transportin 2 antibody; Transportin-2 antibody; TRN2 antibody, karyopherin beta 2b), karyopherin beta 2b) antibody; Transportin 2 (Importin 3, transportin antibody; Karyopherin beta-2b antibody; KPNB2B antibody; Tnpo2 antibody; TNPO2_HUMAN antibody; Transportin 2 (importin 3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Human TNPO2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14787 |
Uniprot Id
O14787
Target Species
Human
Target Name
TNPO2
Target Full Name
Transportin-2
Target Function
Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Importin beta family, Importin beta-2 subfamily
Target Synonyms
Importin 3; IPO3; Karyopherin beta 2b, transportin; Karyopherin beta-2b; KPNB2B; Tnpo2; TNPO2_HUMAN; Transportin 2 (importin 3, karyopherin beta 2b); Transportin 2 (Importin 3, karyopherin beta 2b), isoform CRA b; Transportin 2; Transportin-2; TRN2
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