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Rabbit anti-Human SHKBP1 Polyclonal Antibody

The antibody against SHKBP1 was raised in rabbit using the Human SHKBP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51876A

The antibody against SHKBP1 was raised in rabbit using the Human SHKBP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-51876A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSHKBP1
Target SynonymsPP203 antibody; Sb1 antibody; SH3KBP1 binding protein 1 antibody; SH3KBP1-binding protein 1 antibody; SHKB1_HUMAN antibody; SHKBP1 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman SHKBP1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8TBC3
Background Information
  • Uniprot Id

    Q8TBC3

  • Target Species

    Human

  • Target Name

    SHKBP1

  • Target Full Name

    SH3KBP1-binding protein 1

  • Target Function

    Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.

  • Target Subcellular Location

    Lysosome.

  • Target Protein Families

    KCTD3 family

  • Target Tissue Specificity

    Widely expressed.

  • Target Synonyms

    PP203; Sb1; SH3KBP1 binding protein 1; SH3KBP1-binding protein 1; SHKB1_HUMAN; SHKBP1

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